For children younger than 16 years of age, in whom fluoroquinolones are
For the past 30 years, randomized controlled trials have consistently and clearly demonstrated that antibiotics shorten the duration of illness and alleviate the disability associated with travelers’ diarrhea (TD)
military personnel in Thailand presenting with the acute onset of diarrhea were randomized to treatment with one of 3 regimens: a single 1 g dose of azithromycin, 500 mg of azithromycin daily for 3 days, or 500 mg levofloxacin daily for 3 days
Conclusions
Younger children are at especially high risk of acquiring travellers’ diarrhea and of suffering more severe consequences
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Azithromycin The simplest azithromycin treatment regimen is a single dose of 1,000 mg, but side effects (mainly nausea) can limit the acceptability of this large dose; taking the medication as 2 divided doses on the same day 6 months or older: For 1-day regimen: 30 mg/kg orally as a single dose
Conclusions
Travelers’ diarrhea (TD) is the most predictable travel-related illness
Levofloxacin and ciprofloxacin are also options for acute watery diarrhea (single dose 500 mg and 750 mg, respectively) and febrile diarrhea Traveler’s diarrhea is an infection characterized by diarrhea, nausea, and vomiting that commonly occur in travelers to areas of the world with poor water purification
The message For the treatment of travelers' diarrhea in an Escherichia coli predominant region of the world, a single 500 mg dose of azithromycin appeared as effective as a 1,000 mg dose
Children 6 months of age and older weighing less than 34 kg—Dose is based on body weight and must be determined by your doctor